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  • RESEARCH HIGHLIGHT

An antibody joins forces with the pancreas to delay diabetes

An immune molecule props up cells that make insulin, thereby restoring production of the crucial hormone.
Light micrograph of a section through an islet of Langerhans in pancreas tissue.

Insulin-producing cells (purple cells in pale area) in the pancreas are rejuvenated by the antibody teplizumab. Credit: CNRI/Science Photo Library

An antibody previously shown to stave off type 1 diabetes produces its benefits by shoring up the function of insulin-making cells — an effect strong enough to partially reverse problems with the body’s insulin supply.

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Nature 591, 180 (2021)

doi: https://doi.org/10.1038/d41586-021-00588-w

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