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Ten computer codes that transformed science

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Nature 589, 344-348 (2021)


Updates & Corrections

  • Correction 22 January 2021: An earlier version of this feature erroneously stated that Paul Ginsparg migrated an early version of the arXiv preprint sharing system to the Internet.

  • Update 19 February 2021: This article has been updated with data from a survey that asked readers to weigh in on the codes selected in the Feature (see ‘Top choices for science code’ and ‘Overlooked software’).

  • Correction 08 April 2021: An earlier version of this story erred in describing the IPython Notebook development team and the size of the first version that was released.


  1. The Event Horizon Telescope Collaboration et al. Astrophys. J. Lett. 875, L1 (2019).

    Article  Google Scholar 

  2. Braig, K., Adams, P. D. & Brünger, A. T. Nature Struct. Biol. 2, 1083–1094 (1995).

    Article  PubMed  Google Scholar 

  3. Strasser, B. J. J. Hist. Biol. 43, 623–660 (2010).

    Article  PubMed  Google Scholar 

  4. Newmark, P. Nature 304, 108 (1983).

    Article  PubMed  Google Scholar 

  5. Manabe, S. & Bryan, K. J. Atmos. Sci. 26, 786–789 (1969).

    Article  Google Scholar 

  6. Lawson, C. L., Hanson, R. J., Kincaid, D. R. & Krogh, F. T. ACM Trans. Math. Software 5, 308–323 (1979).

    Article  Google Scholar 

  7. Ginsparg, P. Preprint at (2011).

  8. Nature Photon. 6, 1 (2012).

    Article  Google Scholar 

  9. Nature 563, 145–146 (2018).

    Article  PubMed  Google Scholar 

  10. Krizhevsky, A., Sutskever, I. & Hinton, G. E. in Proc. 25th Int. Conf. Neural Information Processing Systems (eds Pereira, F., Burges, C. J. C., Bottou, L. & Weinberger, K. O.) 1097–1105 (Curran Associates, 2012).

    Google Scholar 

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