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The secret forces that squeeze and pull life into shape

Microscopic image of a zebrafish embryo 22 hours postfertilization

Developing embryos, such as this zebrafish, rely on physical forces to sculpt them as they grow. Credit: Philipp Keller/HHMI Janelia Research Campus

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Nature 589, 186-188 (2021)



  1. Schliffka, M. F. et al. Preprint at bioRxiv (2020).

  2. Dumortier, J. G. et al. Science 365, 465–468 (2019).

    Article  PubMed  Google Scholar 

  3. Serwane, F. et al. Nature Methods 14, 181–186 (2017).

    Article  PubMed  Google Scholar 

  4. Mongera, A. et al. Nature 561, 401–405 (2018).

    Article  PubMed  Google Scholar 

  5. Zhang, S., Teng, X., Toyama, Y. & Saunders, T. E. Curr. Biol. 30, 3364–3377 (2020).

    Article  PubMed  Google Scholar 

  6. Koser D. E. et al. Nature Neurosci. 19, 1592–1598 (2016).

    Article  PubMed  Google Scholar 

  7. Thompson, A. J. et al. eLife 8, e39356 (2019).

    Article  PubMed  Google Scholar 

  8. Aragona, M. et al. Nature 584, 268–273 (2020).

    Article  PubMed  Google Scholar 

  9. Fiore, V. F. et al. Nature 585, 433–439 (2020).

    Article  PubMed  Google Scholar 

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