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Why Oxford’s positive COVID vaccine results are puzzling scientists

Preliminary data suggest that the immunization was more effective in trial participants who received a lower dose.
  1. Ewen Callaway
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A highly anticipated COVID-19 vaccine has delivered some encouraging — but head-scratching — results. The vaccine developed by the University of Oxford, UK, and pharmaceutical giant AstraZeneca was found to be, on average, 70% effective in a preliminary analysis of phase III trial data, the developers announced in a press release on 23 November.

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Nature 588, 16-18 (2020)

doi: https://doi.org/10.1038/d41586-020-03326-w

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