Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
Twenty years ago this week, on 2 November 2000, one astronaut and two cosmonauts opened the door to the newly constructed International Space Station (ISS) and floated in. It was the beginning of two decades of humans permanently living and working aboard the orbiting outpost.