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Huge virus’s mini-enzymes boost CRISPR’s powers

3D render of a purple enzyme using an orange guide RNA to split apart and cut the strands of a green DNA helix.

A CRISPR–Cas complex (purple and orange) edits a strand of DNA (green). An ultrasmall version of the Cas enzyme that cuts the DNA could make editing easier. Credit: Getty

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Nature 583, 495 (2020)




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