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Scientists make precise gene edits to mitochondrial DNA for first time

Weird enzyme enables researchers to study — and potentially treat — deadly diseases.
  1. Heidi Ledford
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A peculiar bacterial enzyme has allowed researchers to achieve what even the popular CRISPR–Cas9 genome-editing system couldn’t manage: targeted changes to the genomes of mitochondria, cells’ crucial energy-producing structures.

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Nature 583, 343 (2020)

doi: https://doi.org/10.1038/d41586-020-02054-5

Read the related News & Views, ‘Mitochondrial genome editing gets precise’.

References

  1. Mok, B. Y. et al. Nature https://10.1038/s41586-020-2477-4 (2020).

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