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Daily briefing: Why the coronavirus death toll in Wuhan, China, has just jumped by 50%
The addition of deaths of people at home and at medical institutions that weren’t reporting data has added another 1,300 fatalities to the official count. Plus: NASA’s soaringly ambitious plan to bring back rocks from Mars and apple hunters rediscover ten lost varieties.
The US and European space agencies have unveiled a daring plan to bring the first rocks back from Mars. The samples will be collected by NASA’s Perseverance rover, which is due to launch in the coming months. The ambitious interplanetary pilgrimage to return the rocks will involve two spacecraft that travel to Mars in 2026: a small rocket that will blast off the Martian surface, carrying the rocks into orbit, where a second craft will take them and fly back to Earth by 2031. “This is by no means a simple task,” says Jim Watzin, head of NASA’s Mars exploration programme in Washington DC. “But we have kept it as simple as possible.”
A volunteer-run organization has rediscovered 10 lost apple varieties in the northwestern United States. The Lost Apple Project seeks to rescue some of the 17,000 apple cultivars thought to have once been grown in North America, of which only about 4,500 are known to exist today. Members use old maps, county-fair records, newspaper clippings and nursery sales ledgers to find abandoned orchards and collect fruits. They then ship them to an Oregon conservancy, where they are studied. The organization also tries to reconstruct the history of the orchards. “When I find an apple that’s lost, I want to know who homesteaded it, when they were there, who their children were, when they took their last drink of water,” says amateur botanist E. J. Brandt.
Most people infected on aircraft carrier have no symptoms
The US aircraft carrier Theodore Roosevelt has become another natural experiment for the transmission of COVID-19. The Navy has tested almost the entire crew after one member died from the disease. Many who tested positive had no symptoms, just like on the cruise ship Diamond Princess. On the cruise, which was packed with older people, the asymptomatic proportion was 18%. On the aircraft carrier — unsurprisingly home to mostly young, healthy people — it was 60%. “We’re learning that stealth in the form of asymptomatic transmission is this adversary’s secret power,” said Rear Admiral Bruce Gillingham, surgeon general of the Navy. (Reuters | 3 min read)
Wisps of hope for remdesivir
The researcher overseeing a closely watched clinical trial in Chicago has indicated that the antiviral medicine remdesivir might be showing positive signs against COVID-19. More than 100 people, most with severe disease, were treated with daily infusions of remdesivir (there was no control group). “Overall our patients have done very well,” infectious-disease specialist Kathleen Mullane told colleagues in an internal video call. Study leaders urge extreme caution about these preliminary and as-yet-unpublished results. (STAT | 5 min read)
Watching the wave engulf New York
Emergency-room physician Helen Ouyang describes how she went from hearing how the coronavirus outbreak overwhelmed hospitals in Lombardy, Italy, to seeing it happen first-hand in her hospital in New York. “It has been less than six weeks, but I’ve never felt less useful as a doctor,” writes Ouyang. “The one thing I can do — what I think will matter most, in the end — is just to be a person.” (The New York Times | 43 min read)
Oncologist Charlie Swanton shares how researchers at one of Europe’s largest biomedical-research centres, the Francis Crick Institute, have retooled their cancer lab into a diagnostic-testing facility. (Nature | 4 min read)
Video of the week
Physicists have found the strongest evidence yet that neutrinos are fundamentally different from their antimatter counterparts. Researchers at the Super-Kamiokande detector in Japan found that one flavour of neutrino — muons — morphed into different types of particle at a different rate than did their antimatter twins. If confirmed, the results could help to solve the Universe’s greatest mystery: why there is more matter than antimatter. (Nature | 4 min video)
Donald Knuth’s earliest claim to fame was at age 13, when he won a contest by finding 4,700 anagrams for ‘Ziegler’s Giant Bar’ — and was awarded chocolate for his entire class. It was only the first of many honours that would come to include the A. M. Turing Award, the most prestigious in computer science. Knuth describes his multi-volume opus-in-progress, The Art of Computer Programming, as a manifesto for writing code so beautiful that it can be read by humans like a story. “It describes the way I love to do math and the way I wish I had been taught.”
“Since January, I have spent every day alone in my laboratory, urgently trying to find a cure for COVID‑19,” says structural biologist and pharmacologist Li Hua, who lives on campus at Huazhong University of Science and Technology in Wuhan, China, the epicentre of the pandemic. Li’s colleagues, who had left for the Lunar New Year holiday, could not return during the lockdown and he is currently the only one who can access the lab. Now the lockdown there has ended, Li is working with collaborators in Shanghai to test the efficacy of the drug candidates he identified. (Nature | 3 min read)
A rarely seen view of the top of one of Stonehenge’s giant sarsen stones reveals familiar-looking tenons and holes. (Stonehenge on Twitter)
doi: https://doi.org/10.1038/d41586-020-01142-w
We have a winner! Our roaming Rockhopper shall be known henceforth as Leif Penguinson. Let songs be sung to the glory of reader Nigeala Nigrath for the suggestion!
This week, we look back on the time Leif Penguinson joined the Apollo 15 mission to the Moon. Good times! But can you spot the penguin? The answer will be in Monday’s email, all thanks to Briefing photo editor Tom Houghton.
Please let me know how you think Leif survived on the Moon without a spacesuit (or any other feedback on this newsletter) at briefing@nature.com.
Flora Graham, senior editor, Nature Briefing
With contributions by Nicky Phillips and Davide Castelvecchi