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Daily briefing: First coronavirus vaccine clinical trials begin in United States
The phase I trial of the vaccine from drug company Moderna is just the beginning of a long process to test safety and efficacy. Plus: a ‘completely accidental’ discovery hints at how to use standard silicon microchips in a quantum computer and a year without conferences raises the question of whether we need them at all.
Researchers have discovered “by complete accident” a way to control the nucleus of a single atom using only electric fields. Theorists predicted in 1958 that an oscillating electric field could flip a nucleus, but it had never been observed. The finding hints that it might be possible to use standard silicon microchips as the quantum bits, or qubits, in a quantum computer without messing around with difficult-to-constrain magnetic fields.
• The first phase I clinical trial for a potential COVID-19 vaccine has begun in Seattle, Washington. Over the next 6 weeks, 45 participants will receive varying first doses of the vaccine, followed by a second dose 28 days later. They will then be assessed over a 14-month period. The experimental vaccine relies on messenger RNA, which directs the body to make a protein found on the new coronavirus's outer shell — hopefully eliciting an immune response that protects against infection. (Nature | Continuously updated)
• The decision to close schools to slow the spread of COVID-19 weighs heavily on the shoulders of governments who must consider the risk to teaching staff, the impact on students and how childcare needs might hinder essential workers or expose older family members to infection. The US Centers for Disease Control and Prevention says that evidence from other countries shows that places where schools were closed, such as Hong Kong, “have not had more success in reducing spread than those that did not”, such as Singapore. (The Washington Post | 8 min read)
A barrage of fake responses to her online questionnaire prompted quantitative psychologist Melissa Simone to learn how to quash survey-ruining bots. Her tips for protecting your own survey includes using unique, personalized links and including ‘honeypot’ questions that only bots can see.
Lego bricks washed up on British beaches indicate that they could survive in the ocean for up to 1,300 years, says environmental scientist Andrew Turner. (Independent)
Cellist Yo-Yo Ma has kicked off a campaign to share #SongsOfComfort on Twitter with performances including Bach’s Cello Suite No. 3 dedicated to healthcare workers. If pop is more your thing, here’s a BBC round-up of online ad-hoc concerts from bands including Christine and the Queens.
Tell me your favourite working-from-home tunes — and any other feedback on this newsletter —at briefing@nature.com. And if you are not so comfortably ensconced, or you are facing difficulties, you have my very best wishes.