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Major HIV vaccine study fails
An ambitious HIV vaccine trial in South Africa has been halted early after the treatment was deemed to have no efficacy compared to a placebo. The study examined the ‘prime boost’ strategy, in which participants received a pair of complementary HIV vaccines. A smaller study in Thailand a decade ago showed lacklustre results, but researchers still held out hope based on results in monkeys. “It’s a huge disappointment,” says physician-scientist Glenda Gray, who headed the curtailed study. “I was catatonic.”
Features & opinion
Tech tools for open and inclusive labs
Apps and software tools are helping many inclusivity-minded group leaders to transform research from an isolated pursuit into a more open, collective exercise. Messaging platforms to make discussions more transparent, video conferencing for offsite lab members and software to support people with learning differences can all contribute. Plus, there are lower-tech solutions, such as posting your lab’s code of conduct on a public-facing website.
Design your own doctoral project
Instead of looking for PhD positions, why not design your own, suggests fisheries researcher Jesko Becker. He reveals how he created his dream doctoral project in his perfect location — and outlines hurdles to watch out for.
How to master the art of prioritization
Business researcher Carsten Lund Pedersen has come up with a simple tool to help scientists pick, prioritize and pursue the right research project. The project-management triangle measures three key constraints that researchers should consider: ambition, time and energy. "We need to be making clever choices on tricky trade-offs," says Pederson.