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A watershed moment for protein structure prediction

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Nature 577, 627-628 (2020)



  1. Senior, A. W. et al. Nature 577, 706–710 (2020).

    Article  Google Scholar 

  2. Guvench, O. & MacKerell, A. D. Jr Methods Mol. Biol. 443, 63–88 (2008).

    PubMed  Article  Google Scholar 

  3. Maximova, T., Moffatt, R., Ma, B., Nussinov, R. & Shehu, A. PLoS Comput. Biol. 12, e1004619 (2016).

    PubMed  Article  Google Scholar 

  4. Bryngelson, J. D., Onuchic, J. N., Socci, N. D. & Wolynes, P. G. Proteins 21, 167–195 (1995).

    PubMed  Article  Google Scholar 

  5. Marks, D. S. et al. PLoS ONE 6, e28766 (2011).

    PubMed  Article  Google Scholar 

  6. Jones, D. T., Buchan, D. W. A., Cozzetto, D. & Pontil, M. Bioinformatics 28, 184–190 (2012).

    PubMed  Article  Google Scholar 

  7. Kamisetty, H., Ovchinnikov, S. & Baker, D. Proc. Natl Acad. Sci. USA 110, 15674–15679 (2013).

    PubMed  Article  Google Scholar 

  8. Lapedes, A. S., Giraud, B. G., Liu, L. & Stormo, G. D. IMS Lecture Notes Monogr. Ser. 33, 236–256 (1999).

    Article  Google Scholar 

  9. Wang, S., Sun, S., Li, Z., Zhang, R. & Xu, J. PLoS Comput. Biol. 13, e1005324 (2017).

    PubMed  Article  Google Scholar 

  10. Hills, R. D. & Brooks, C. L. Int. J. Mol. Sci. 10, 889–905 (2009).

    PubMed  Article  Google Scholar 

  11. AlQuraishi, M. Cell Syst. 8, 292–301 (2019).

    PubMed  Article  Google Scholar 

  12. Ingraham, J., Riesselman, A., Sander, C. & Marks, D. in 7th Int. Conf. Learn. Represent. (2019).

Download references


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