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How evolution builds genes from scratch

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Nature 574, 314-316 (2019)

doi: https://doi.org/10.1038/d41586-019-03061-x

Updates & Corrections

  • Clarification 13 November 2019: After publication of our story, we learnt that another scientist had suggested the de novo origin of antifreeze protein genes before Helle Baalsrud’s team.

References

  1. Baalsrud, H. T. et al. Mol. Biol. Evol. 35, 593–606 (2018).

    Article  Google Scholar 

  2. Zhuang, X. Creating sense from non-sense DNA: de novo genesis and evolutionary history of antifreeze glycoprotein gene in northern codfishes (gadidae). PhD thesis, Univ. Illinois, Urbana-Champaign (2014).

  3. Ohno, S. Evolution by Gene Duplication (Springer, 1970).

    Google Scholar 

  4. Begun, D. J., Lindfors, H. A., Thompson, M. E. & Holloway, A. K. Genetics 172, 1675–1681 (2006).

    Article  PubMed  Google Scholar 

  5. Begun, D. J., Lindfors, H. A., Kern, A. D. & Jones, C. D. Genetics 176, 1131–1137 (2007).

    Article  PubMed  Google Scholar 

  6. Albà, M. M. & Castresana, J. Mol. Biol. Evol. 22, 598–606 (2005).

    Article  PubMed  Google Scholar 

  7. Carvunis, A.-R. et al. Nature 487, 370–374 (2012).

    Article  PubMed  Google Scholar 

  8. Knopp, M. et al. mBio 10, e00837-19 (2019).

    Article  PubMed  Google Scholar 

  9. Neme, R., Amador, C., Yildirim, B., McConnell, E. & Tautz, D. Nature Eco. Evol. 1, 0127 (2017).

    Article  Google Scholar 

  10. Zhang, L. et al. Nature Ecol. Evol. 3, 679–690 (2019).

    Article  PubMed  Google Scholar 

  11. Toll-Riera, M. et al. Mol. Biol. Evol. 26, 603–612 (2009).

    Article  PubMed  Google Scholar 

  12. Wu, D.-D., Irwin, D. M. & Zhang, Y.-P. PLoS Genet. 7, e1002379 (2011).

    Article  PubMed  Google Scholar 

  13. Casola, C. Genome Biol. Evol. 10, 2906–2918 (2018).

    PubMed  Google Scholar 

  14. Li, C.-Y. et al. PLoS Comput. Biol. 6, e1000734 (2010).

    Article  PubMed  Google Scholar 

  15. Wang, D., Ma, J. Z. & Li, M. D. Pharmacogenomics J. 5, 166–172 (2005).

    Article  PubMed  Google Scholar 

  16. Suenaga, Y. et al. PLoS Genet. 10, e1003996 (2014).

    Article  PubMed  Google Scholar 

  17. Willemsen, A., Félez-Sánchez, M. & Bravo, I. G. Genome Biol. Evol. 11, 1602–1617 (2019).

    Article  PubMed  Google Scholar 

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