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Scientists rise up against statistical significance

Illustration by David Parkins

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Nature 567, 305-307 (2019)



  1. Fisher, R. A. Nature 136, 474 (1935).

    Article  Google Scholar 

  2. Schmidt, M. & Rothman, K. J. Int. J. Cardiol. 177, 1089–1090 (2014).

    Article  PubMed  Google Scholar 

  3. Wasserstein, R. L., Schirm, A. & Lazar, N. A. Am. Stat. (2019).

    Article  Google Scholar 

  4. Hurlbert, S. H., Levine, R. A. & Utts, J. Am. Stat. (2019).

    Article  Google Scholar 

  5. Lehmann, E. L. Testing Statistical Hypotheses 2nd edn 70–71 (Springer, 1986).

    Google Scholar 

  6. Gigerenzer, G. Adv. Meth. Pract. Psychol. Sci. 1, 198–218 (2018).

    Article  Google Scholar 

  7. Greenland, S. Am. J. Epidemiol. 186, 639–645 (2017).

    Article  PubMed  Google Scholar 

  8. McShane, B. B., Gal, D., Gelman, A., Robert, C. & Tackett, J. L. Am. Stat. (2019).

    Article  Google Scholar 

  9. Gelman, A. & Loken, E. Am. Sci. 102, 460–465 (2014).

    Article  Google Scholar 

  10. Amrhein, V., Trafimow, D. & Greenland, S. Am. Stat. (2019).

    Article  Google Scholar 

Download references

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  1. Supp info for Amrhein et al Comment_data V2


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