Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • COMMENT

Adopt a moratorium on heritable genome editing

Nature 567, 165-168 (2019)

doi: https://doi.org/10.1038/d41586-019-00726-5

References

  1. Araki, M. & Ishii, T. Reprod. Biol. Endocrinol. 12, 108 (2014).

    Article  PubMed  Google Scholar 

  2. Pontin, J. ‘The Genetics (and Ethics) of Making Humans Fit for Mars’ Wired (8 July 2018).

  3. Regalado, A. ‘The DIY designer baby project funded with Bitcoin’ MIT Technol. Rev. (1 February 2019).

  4. Hurlbut, J. B. Nature 565, 135 (2019).

    Article  PubMed  Google Scholar 

  5. National Academies of Sciences, Engineering, and Medicine. Human Genome Editing: Science, Ethics, and Governance (National Academies Press, 2017).

    Google Scholar 

  6. Costas, J. Am. J. Med. Genet. B Neuropsychiatr. Genet. 177, 274–283 (2018).

    Article  PubMed  Google Scholar 

  7. Joy, M. T. et al. Cell 176, 1143–1157 (2019).

    Article  PubMed  Google Scholar 

  8. Steffann, J., Jouannet, P., Bonnefont, J. P., Chneiweiss, H. & Frydman, N. Cell Stem Cell 22, 481–482 (2018).

    Article  PubMed  Google Scholar 

  9. Jasanoff, S. & Hurlbut, J. B. Nature 555, 435–437 (2018).

    Article  PubMed  Google Scholar 

  10. Langlois, A. Palgrave Commun. 3, 17019 (2017).

    Article  PubMed  Google Scholar 

  11. Burall, S. Nature 555, 438–439 (2018).

    Article  PubMed  Google Scholar 

  12. Baylis, F. Nature Hum. Behav. 1, 0103 (2017).

    Article  Google Scholar 

  13. Hurlbut, J. B. et al. Trends Biotechnol. 36, 639–641 (2018).

    Article  PubMed  Google Scholar 

  14. Saha, K. et al. Trends Biotechnol. 36, 741–743 (2018).

    Article  PubMed  Google Scholar 

Download references

Competing Interests

Eric Lander (E.L.) notes that institutions with which he is associated — Broad Institute, MIT and Harvard — have interests in CRISPR technology, including patents and patent applications, and that he is a co-inventor on certain patents and patent applications relating to CRISPR-based gene-editing technologies. He also serves on the board of directors for Codiak BioSciences and Neon Therapeutics, and serves on the scientific advisory board of F-Prime Capital Partners and Third Rock Ventures. Feng Zhang (F.Z.) is a founder and scientific adviser for Editas Medicine, Beam Therapeutics, Arbor Biotechnologies, and Pairwise Plants. F.Z. is also an inventor on a number of issued patents and applications relating to CRISPR-based gene-editing technologies. Emmanuelle Charpentier (E.C.) is a co-founder of CRISPR Therapeutics and ERS Genomics and is a member of the scientific advisory board of CRISPR Therapeutics. J. Keith Joung (J.K.J.) has financial interests in Beam Therapeutics, Editas Medicine, Endcadia, EpiLogic Therapeutics, Pairwise Plants, Poseida Therapeutics, and Transposagen Biopharmaceuticals. J.K.J.’s interests were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict of interest policies. J.K.J. is a member of the board of directors of the American Society of Gene and Cell Therapy. J.K.J. is a co-inventor on various patents and patent applications that describe gene-editing technologies. David R. Liu (D.R.L.) is a consultant and co-founder of Beam Therapeutics, Editas Medicine, and Pairwise Plants, companies that use genome editing, and is a co-inventor on genome editing patents. Complete financial disclosures are available at https://liugroup.us/david-r-liu/. Wensheng Wei (W.W.) serves as a scientific adviser for EdiGene.

Subjects

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links