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‘Invisible’ mice reveal anatomical secrets

Technique that turns dead rodents clear uncovers surprising details about how the animals respond to injury.
  1. Sara Reardon
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A new technique that makes dead mice transparent and hard like plastic is giving researchers an unprecedented view of how different types of cell interact in the body. The approach lets scientists pinpoint specific tissues within an animal while scanning its entire body.

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Nature 563, 305-306 (2018)

doi: https://doi.org/10.1038/d41586-018-07336-7

References

  1. Pan, C. et al. Nature Methods 13, 859–867 (2016).

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  2. Louveau, A. et al. Nature 523, 337–341 (2015).

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  3. Cai, R. et al. Preprint at bioRxiv https://doi.org/10.1101/374785 (2018).

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