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The unexpected role of histones in childhood brain cancer

Brain tumours in children differ fundamentally from those in adults — a discovery with enormous implications for treatment strategies.
  1. Liam Drew

    1. Liam Drew is a freelance science writer based in London.

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Under a microscope, gliomas from children and adults are indistinguishable. The cells of such brain tumours resemble glia, the non-neuronal cells of the brain. And in the most aggressive type of these tumours, known as high-grade glioma (HGG), the same telltale signs of rapid proliferation are observed in the young and the old, alike. Tumours in the brains of both groups are nourished by networks of blood vessels and peppered with pockets of cell death.

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Nature 561, S56-S58 (2018)

doi: https://doi.org/10.1038/d41586-018-06712-7

This article is part of Nature Outlook: Brain cancer, an editorially independent supplement produced with the financial support of third parties. About this content.

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