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Controversial CRISPR ‘gene drives’ tested in mammals for the first time

Experiments in mice suggest that the technology has a long way to go before being used for pest control in the wild.
  1. Ewen Callaway
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A controversial technology capable of altering the genomes of entire species has been applied to mammals for the first time. In an article posted1 on the bioRxiv preprint server on 4 July, researchers describe developing ‘gene drives’ — which could be used to eradicate problematic animal populations — in lab mice using the CRISPR gene-editing technique.

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Nature 559, 164 (2018)

doi: https://doi.org/10.1038/d41586-018-05665-1

References

  1. Grunwald, H. A. et al. Preprint on bioRxiv https://doi.org/10.1101/362558 (2018).

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