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Histidine metabolism boosts cancer therapy

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Nature 559, 484-485 (2018)



  1. Kanarek, N. et al. Nature 559, 632–636 (2018).

    Article  Google Scholar 

  2. Farber, S., Diamond, L. K., Mercer, R. D., Sylvester, R. F. Jr & Wolff, J. A. N. Engl. J. Med. 238, 787–793 (1948).

    PubMed  Article  Google Scholar 

  3. Assaraf, Y. G. & Schimke, R. T. Proc. Natl Acad. Sci. USA 84, 7154–7158 (1987).

    PubMed  Article  CAS  Google Scholar 

  4. Roberts, K. G. et al. N. Engl. J. Med. 371, 1005–1015 (2014).

    PubMed  Article  Google Scholar 

  5. Locasale, J. W. Nature Rev. Cancer 13, 572-583 (2013).

    PubMed  Article  Google Scholar 

  6. Institute of Medicine of the National Academies. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids Ch. 10 (Natl Acad. Press, 2005).

    Google Scholar 

  7. Brown, P. M., Pratt, A. G. & Isaacs, R. G. Nature Rev. Rheumatol. 12, 731–742 (2016).

    PubMed  Article  CAS  Google Scholar 

Download references


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