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  • RESEARCH HIGHLIGHT

A short course of laxatives has long-lasting effects on microbiome

Drugs prompt some gut bacteria to vanish in mice.
Fluorescence images of host nuclei flattened during diarrhoea

The nuclei (blue) in the gut cells of mice treated with laxatives become flatter (right) than those of untreated mice (left). Credit: C. Tropini et al./Cell

A widely used laxative creates profound changes in the gut microbiome, according to experiments in mice.

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Nature 558, 488-489 (2018)

doi: https://doi.org/10.1038/d41586-018-05480-8

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