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Giving at-risk children pre-emptive antibiotics reduces deaths

Clinical trial in Africa helps kids, but raises fears about drug resistance.
  1. Amy Maxmen
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To stem the rise in antibiotic resistance, researchers recommend that people only take the drugs after they are diagnosed with a bacterial infection. But a trial involving nearly 200,000 children in Niger, Tanzania and Malawi went against that guidance in an attempt to save youngsters in regions where as many as one in ten die before their fifth birthday.

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Nature 557, 14-15 (2018)

doi: https://doi.org/10.1038/d41586-018-04962-z

References

  1. Keenan, J. D. et al. N. Engl. J. Med. http://dx.doi.org/10.1056/NEJMoa1715474 (2018).

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  2. Porco, T. C. et al. J. Am. Med. Assoc. 302, 962–968 (2009).

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