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A woman jogging on a bridge

The effect of strenuous exertion on food intake has been traced to specific brain cells in mice. Credit: RooM the Agency/Alamy

Neuroscience

Why a sweaty workout dampens appetite

A rise in body temperature directly affects brain cells that regulate eating.

Exercise suppresses eating by heating up a region of the brain called the hypothalamus, according to a study in mice.

Although it has long been clear that exercise can reduce appetite, the mechanism behind this effect has not been clear. Young-Hwan Jo and his colleagues at the Albert Einstein College of Medicine in New York City found that a class of brain cells in the hypothalamus that affect appetite also bear proteins called TRPV1-like receptors. These receptors respond to changes in temperature.

The team found that, in mice, a stint on the treadmill both raised the temperature of the hypothalamus and reduced eating. The same dual effect was seen after artificial stimulation of the neurons that express TRPV1-like receptors. Conversely, when the researchers turned down expression of the neurons’ Trpv1 gene, mice did not curb their food intake after exercise.

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Plastic detritus from snacks and meals floats in the Red Sea. Marine sampling shows that food waste accounts for nearly 90% of plastic pollution at some locales. Credit: Andrey Nekrasov/Barcroft Media/Getty

Ocean sciences

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Quantum information

Quantum keys dial up tamper-proof conference calls

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Economics

Poor harvest: farmers earn a pitiful fraction of the money spent on food

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A woman wearing a protective face mask splashes her hands in a jet of water

A pedestrian seeks relief from searing temperatures in Spain, where a high proportion of heat-related deaths have been linked to climate change. Credit: SALAS/EPA-EFE/Shutterstock

Climate change

More than one-third of heat deaths blamed on climate change

Warming resulting from human activities accounts for a high percentage of heat-related deaths, especially in southern Asia and South America.
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