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How the immune system could stymie some CRISPR gene therapies

Researchers hoping to use a gene-editing technique to treat diseases may have to seek alternative enzymes.
  1. Heidi Ledford
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Hopes are high that CRISPR–Cas9 could one day be used in people to correct mutations that cause disease. But the new study, which was published on the preprint server bioRxiv and has not yet been peer-reviewed, is generating questions about whether this approach will succeed.

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doi: https://doi.org/10.1038/d41586-018-00335-8

References

  1. Charlesworth, C. T. et al. Preprint at bioRxiv http://dx.doi.org/10.1101/243345 (2018).

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