Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News And Views
  • Published:

How T cells spot tumour cells

Immunotherapy can reawaken T cells to destroy tumour cells. Modelling of tumour and T-cell interactions suggests why certain tumour cells are targeted and improves predictions of immunotherapy outcome.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. Balachandran, V. P. et al. Nature 551, 512–516 (2017).

    Article  CAS  ADS  Google Scholar 

  2. Łuksza, M. et al. Nature 551, 517–520 (2017).

    Article  ADS  Google Scholar 

  3. Robins, H. Curr. Opin. Immunol. 25, 646–652 (2013).

    Article  CAS  Google Scholar 

  4. Sharma, P. & Allison, J. P. Science 348, 56–61 (2015).

    CAS  ADS  Google Scholar 

  5. Schumacher, T. N. & Hacohen, N. Curr. Opin. Immunol. 41, 98–103 (2016).

    Article  CAS  Google Scholar 

  6. Carreno, B. M. et al. Science 348, 803–808 (2015).

    Article  CAS  ADS  Google Scholar 

  7. Ott, P. A. et al. Nature 547, 217–221 (2017).

    Article  CAS  ADS  Google Scholar 

  8. Sahin, U. et al. Nature 547, 222–226 (2017).

    Article  CAS  ADS  Google Scholar 

Download references


Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sarkizova, S., Hacohen, N. How T cells spot tumour cells. Nature 551, 444–446 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer