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Organoids identify a role for IL-7 in coeliac disease

  1. Yvonne Bordon
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Reporting in Nature, Santos et al. have used human organoids generated from individuals with coeliac disease to identify an unexpected role for IL-7 in the pathogenesis of this disease.

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Nature Reviews Drug Discovery 23, 741 (2024)

doi: https://doi.org/10.1038/d41573-024-00143-y

This article originally appeared in Nat. Rev. Immunol. (https://doi.org/10.1038/s41577-024-01082-w)

References

  1. Santos, A. J. M. et al. A human autoimmune organoid model reveals IL-7 function in coeliac disease. Nature 632, 401–410 (2024)

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