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Nature Reviews Drug Discovery 21, 793-794 (2022)
The views and opinions presented here represent those of the authors and should not be considered to represent advice or guidance on behalf of the US Food and Drug Administration.
D.G.B. and H.J.W. are employees of Jnana Therapeutics, which does not have a direct bearing on the subject of this paper. H.J.W is a shareholder in AstraZeneca. The other authors declare no competing interests. This study was supported in part by the Intramural Research Program of the NCATS, NIH.