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The email came out of the blue, titled only “Zoom invite”. But DeepMind’s John Jumper breathed a sigh of relief on opening it. After months of stressing about CASP14 — a biennial competition to predict the structure of proteins on the basis of only their amino acid sequences — the results were clear. His group had “performed amazingly well … both relative to other groups and in absolute model accuracy,” the conference organizers had written.