Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • FROM THE ANALYST'S COUCH

The failure to fail smartly

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Nature Reviews Drug Discovery 20, 259-260 (2021)

doi: https://doi.org/10.1038/d41573-020-00167-0

Acknowledgements

The authors thank the staff of the National Academies Forum on Drug Discovery, Development, and Translation, including C. Shore and A. Wagner Gee, for contributing to the development of the action collaborative and review of this manuscript. Additional thanks go to D. Bearss and J. Mendoza-Torres from the Research Center at the National Academies for providing research support. The authors also thank M.D. Mostats from Amgen for his insight and technical assistance on benchmarking data. They gratefully acknowledge leadership made by the collaborative participants (listed in the supplementary information) and input by the many experts who shared their experience and suggestions on how to improve drug development. Lastly, the authors thank the members of the Forum on Drug, Discovery, Development and Translation for their guidance on developing the action collaborative.

Disclaimer

The Improving the Drug Development Process through Examining Late-Stage Failures Action Collaborative is an ad hoc activity associated with the US National Academies’ Forum on Drug Discovery, Development, and Translation. It does not necessarily represent the views of any one organization, the Forum, or the National Academies and is not subjected to the review procedures of, nor is it a report or product of, the National Academies.

Supplementary Information

  1. Supplementary Box 1

Competing Interests

S.G. is an employee of Amgen. R.C. is an employee of Verily Life Sciences. J.A.W. is an employee of Cygnal Therapeutics. C.P.A and J.A.W. are members of the FNIH Biomarkers Consortium executive committee. E.K., L.D.H. and J.A.D. declare no competing interests.

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links