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Immune agonist antibodies face critical test

Immunotherapies that activate costimulatory receptors on T cells have failed so far in the clinic, but the first phase III trial of an agonist antibody in cancer has just begun and second-generation candidates are advancing.

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Nature Reviews Drug Discovery 19, 3-5 (2020)

doi: 10.1038/d41573-019-00214-5

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