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Microbiome therapeutics go small molecule

Small-molecule drugs and biologics that alter the microbiome or its interaction with host tissues are poised to change the face of microbiome therapeutics.

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Nature Reviews Drug Discovery 18, 569-572 (2019)

Updates & Corrections

  • Correction 12 July 2019: The name of the company Kaleido Biosciences and the status of drug candidates it is developing have been corrected in Table 1, and the indication for SYN-010 has been corrected to irritable bowel syndrome with constipation. It has also been clarified that Zehna Therapeutics and Emily Balskus at Harvard University are both separately developing CutC inhibitors.

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