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Massive NIH–industry project opens portals to target validation

Five years in, the US$360 million Accelerating Medicines Partnership is yielding tools to speed up drug discovery for rheumatoid arthritis, lupus, diabetes, Alzheimer disease and Parkinson disease.
  1. Elie Dolgin
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Credit: Image modified from normaals/iStock/Getty Images Plus

In April 2014, Francis Collins stood before a US Congressional committee and touted the creation of an “unprecedented public–private effort” that would use “cutting-edge scientific approaches to sift through a long list of potential therapeutic targets and biomarkers” and ultimately “treat and cure disease faster”.

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Nature Reviews Drug Discovery 18, 240-242 (2019)

doi: https://doi.org/10.1038/d41573-019-00033-8

Updates & Corrections

  • Clarification 01 March 2019: Clarifications have been made about Regeneron's use of the diabetes portal and about the number of exomes needed to account for more of the genetic underpinnings of diabetes.

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