Figure 2 | Cellular & Molecular Immunology

Figure 2

From: Lineage relationship of CD8+ T cell subsets is revealed by progressive changes in the epigenetic landscape

Figure 2

Correlation between gene expression and histone methylation in signature genes. (A) Heat map of signature genes (defined as those specific to at least one of the T-cell subsets using an ANOVA test at BH-adjusted P <= 0.01). Genes with similar patterns across the cell types are grouped using k-means algorithm and marked by colors alongside the rows. (B) Scatterplot showing H3K4me3 correlation with median signature gene expression and H3K27me3 correlation with median signature gene repression in a population of naïve (red), stem cell memory (green), central memory (blue), and effector memory (purple) CD8+ T cells.

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