Figure 5 | Cell Death & Disease

Figure 5

From: Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer

Figure 5

Silencing NKG2DL-targeting miRNAs in BC cells contributes to immune recognition in vivo. (a) A schematic diagram of the lung clearance assay of BCap37 cells. (b) Representatives flow cytometry results of the isotype IgG group. HeLa cells are shown in gate G, and tested cells (BCap37 or MDA-MB-231) with different treatments are shown in gate H. (c), (d) and (e) The relative ratios of tested cells to HeLa cells in the lungs were calculated in the isotype IgG group (c), anti-NKG2D group (d) and anti-NK1.1 group (e), respectively. For (ce), the ratio of tested cells that treated with control miRNAs to HeLa cells was set to be 100%. Error bars represent the S.D. obtained from three independent experiments. *P<0.05, **P<0.01, ***P<0.001

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