Figure 2 | Cell Death & Differentiation

Figure 2

From: The late stages of autophagy: how does the end begin?

Figure 2

Similarity between autophagosome closure, virus escape and multivesicular body. (a) The isolation membrane/phagophore extends and the leading edge finally closes to complete autophagosome formation. (b) Influenza virus fuses with the endosome and the nucleocapsid is released into the cytoplasm. Topologically, similar membrane structures are found in the events during influenza virus escape from the endosome and in autophagosome formation. However, they occur in reverse order. (c) Multivesicular body generation and back fusion of internal vesicles. Internal vesicles are generated through invagination of the limiting membrane and subsequent scission. In dendritic cells, internal vesicles can back fuse with the limiting membrane

Back to article page