Table 3 Clinical characteristics that supports the stage of stringent complete response according to the IMWG criteria

From: Multiple myeloma patients in long-term complete response after autologous stem cell transplantation express a particular immune signature with potential prognostic implication

N º Isotype EEF IF in serum/urine FLC ratio (0.25-1.66) Cytology: %PC in BM MFC: %PC in BM PC’s IP MRD by MFC
1 BJ κ Normal Polyclonal/negative 1,02 No observed 0,10% Normal Negative
2 BJ λ Normal Polyclonal/negative 0,61 2% 0,40% Normal Negative
3 IgG k Normal Polyclonal/negative 0,97 NA NA NA NA
4 IgG k Normal Polyclonal/negative 0,65 3% 1,30% Normal Negative
5 IgG k Normal Polyclonal/negative 1,15 2% 0,80% Normal Negative
6 IgG κ Normal Polyclonal/negative 0,53 2% 0,30% Normal Negative
7 IgG κ Normal Polyclonal/negative 1,13 2% 0,30% Normal Negative
8 IgG κ Normal Polyclonal/negative 0,81 4% 0,60% Normal Negative
9 IgG κ Normal Polyclonal/negative 0,72 2% 0,80% Normal Negative
10 IgG κ Normal Polyclonal/negative 0,83 1% 0,50% Normal Negative
11 BJ λ Normal Polyclonal/negative 0,88 NA 0,10% Normal Negative
12 IgA λ Normal Polyclonal/negative 0,48 NA NA NA NA
13 IgG k Normal Polyclonal/negative 0,97 2% 0,25% Normal Negative
  1. Abbreviations: BM=bone marrow; EEF=electrophoresis; FLC=free light chains; IF=immunofixation; IP=immunophenotype; MFC=multiparametric flow cytometry; MRD=minimal residual disease; NA=not available; PC=plasma cells.