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References
Kennedy MS, Deeg HJ, Storb R, Doney K, Sullivan KM, Witherspoon RP et al. Treatment of acute graft-versus-host disease after allogeneic marrow transplantation. Randomized study comparing corticosteroids and cyclosporine. Am J Med 1985; 78 (6 Pt 1): 978–983.
Bacigalupo A, van Lint MT, Frassoni F, Podesta’ M, Veneziano G, Avanzi G et al. High dose bolus methylprednisolone for the treatment of acute graft versus host disease. Blut 1983; 46: 125–132.
Wong WM, Wright NA . Epidermal growth factor, epidermal growth factor receptors, intestinal growth, and adaptation. JPEN J Parenter Enteral Nutr 1999; 23 (5 Suppl): S83–S88.
Holtan SG, Verneris MR, Schultz KR, Newell LF, Meyers G, He F et al. Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802. Biol Blood Marrow Transplant 2015; 21: 1029–1036.
Oka Y, Orth DN . Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets. J Clin Invest 1983; 72: 249–259.
Blay J, Brown KD . Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells. J Cell Physiol 1985; 124: 107–112.
Konturek JW, Brzozowski T, Konturek SJ . Epidermal growth factor in protection, repair, and healing of gastroduodenal mucosa. J Clin Gastroenterol 1991; 13 (Suppl 1): S88–S97.
Playford RJ, Wright NA . Why is epidermal growth factor present in the gut lumen? Gut 1996; 38: 303–305.
Oikonomou KA, Kapsoritakis AN, Kapsoritaki AI, Manolakis AC, Tsiopoulos FD, Germenis AE et al. Downregulation of serum epidermal growth factor in patients with inflammatory bowel disease. Is there a link with mucosal damage? Growth Factors 2010; 28: 461–466.
Itoh M, Matsuo Y . Gastric ulcer treatment with intravenous human epidermal growth factor: a double-blind controlled clinical study. J Gastroenterol Hepatol 1994; 9 (Suppl 1): S78–S83.
Sullivan PB, Lewindon PJ, Cheng C, Lenehan PF, Kuo B-S, Haskins JR et al. Intestinal mucosa remodeling by recombinant human epidermal growth factor(1-48) in neonates with severe necrotizing enterocolitis. J Pediatr Surg 2007; 42: 462–469.
Sun J-Z, Lu Y, Xu Y, Liu F, Li F-Q, Wang Q-L et al. Epidermal growth factor receptor expression in acute myelogenous leukaemia is associated with clinical prognosis. Hematol Oncol 2012; 30: 89–97.
Reeves JR, Richards RC, Cooke T . The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis. Br J Cancer 1991; 63: 223–226.
Harandi A, Zaidi AS, Stocker AM, Laber DA . Clinical efficacy and toxicity of anti-EGFR therapy in common cancers. J Oncol 2009; 2009: 567486.
Acknowledgements
We thank Mr Michael Ehrhardt from the Cytokine Reference Laboratory of the University of Minnesota for laboratory analyses. This study was supported in part by the University of Minnesota Masonic Cancer Center, the Office of Research in Women’s Health and the National Institute of Child Health and Human Development, Oregon BIRCWH Award Number 2K12HD043488 (SGH and LFN), the Medical Foundation of Oregon (SGH), and by NIH P30 CA77598 and P01CA111412, utilizing the Biostatistics and Bioinformatics Shared Resource of the Masonic Cancer Center.
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He, F., Verneris, M., Cooley, S. et al. Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 52, 301–303 (2017). https://doi.org/10.1038/bmt.2016.261
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DOI: https://doi.org/10.1038/bmt.2016.261
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