Table 1 Patient characteristics

From: Autologous hematopoietic stem cell transplantation in light chain amyloidosis (AL) with renal involvement

Parameter N (%)/median (range)
Time from Dx to auto-HCT (months) 6.6 (2–120)
Age (years) 58 (41–74)
Male 31 (56)
λ-Light chain subtype 41 (75)
Absolute difference between involved and uninvolved serum-free light chains (dFLC: mg/L) 27 (0–2159)
Median serum albumin before auto-HCT (g/dL) 2.6 (1.5–4.3)
Other visceral organs involved 14 (25)
 Heart 5 (9)
 Liver 5 (9)
 GI 3 (5)
 Peripheral nerves 1 (2)
Induction Rx before auto-HCT 42 (76)
Proteinuria (g/24 h) 5 (0.17–28)
Serum creatinine (mg/dL) 1.20 (0.53–9.28)
2.0 44 (80)
 >2.0 11 (20)
eGFR (mL/min/1.73 m2) 54.6 (10.3–155.4)
Renal stage
 1 16 (29)
 2 27 (49)
 3 11 (20)
 Hemodialysis dependent 2 (4)
  1. Abbreviations: auto-HCT=autologous hematopoietic stem cell transplantation; dFLC=absolute difference between involved and uninvolved serum-free light chains; Dx=diagnosis; eGFR=estimated glomerular filtration rate; GI=gastrointestinal; Rx=treatment.