Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Physician-diagnosed depression and suicides in pediatric hematopoietic cell transplant survivors with up to 40 years of follow-up

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. Packman W, Weber S, Wallace J, Bugescu N . Psychological effects of hematopoietic SCT on pediatric patients, siblings and parents: a review. Bone Marrow Transplant 2010; 45: 1134–1146.

    CAS  Article  Google Scholar 

  2. Sanders JE, Hoffmeister PA, Storer BE, Applebaum FR, Storb RF, Syrjala KL . The quality of life of adult survivors of childhood hematopoietic cell transplant. Bone Marrow Transplant 2010; 45: 746–754.

    CAS  Article  Google Scholar 

  3. Leung W, Hudson MM, Strickland DK, Phipps S, Srivastava DK, Ribeiro RC et al. Late effects of treatment in survivors of childhood acute myeloid leukemia. J Clin Oncol 2000; 18: 3273–3279.

    CAS  Article  Google Scholar 

  4. Meeske KA, Siegel SE, Globe DR, Mack WJ, Bernstein L . Prevalence and correlates of fatigue in long-term survivors of childhood leukemia. J Clin Oncol 2005; 23: 5501–5510.

    Article  Google Scholar 

  5. Zeltzer LK, Lu Q, Leisenring W, Tsao JCI, Recklitis C, Armstrong G et al. Psychosocial outcomes and health-related qualtiy of life in adult childhood cancer survivors: a report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev 2008; 17: 435–446.

    Article  Google Scholar 

  6. Michel G, Rebholz CE, von der Weid NX, Bergstraesser E, Kuehni CE . Psychological distress in adult survivors of childhood cancer: the Swiss Childhood Cancer Survivor study. J Clin Oncol 2010; 28: 1740–1748.

    Article  Google Scholar 

  7. Ferry C, Gemayel G, Rocha V, Labopin M, Esperou H, Robin M et al. Long-term outcomes after allogeneic stem cell transplantation for children with hematological malignancies. Bone Marrow Transplant 2007; 40: 219–224.

    CAS  Article  Google Scholar 

  8. Sun CL, Francisco L, Baker KS, Weisdorf DJ, Forman SJ, Bhatia S . Adverse psychological outcomes in long-term survivors of hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study (BMTSS). Blood 2011; 118: 4723–4731.

    CAS  Article  Google Scholar 

  9. Brinkman TM, Ullrich NJ, Zhang N, Green DM, Zeltzer LK, Lommel KM et al. Prevalence and predictors of prescription psychoactive medication use in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Cancer Surviv 2013; 7: 104–114.

    Article  Google Scholar 

  10. Deyell RJ, Lorenzi M, Ma S, Rassekh SR, Collet JP, Spinelli JJ et al. Antidepressant use among survivors of childhood, adolescent and young adult cancer: a report of the Childhood, Adolescent and Young Adult Cancer Survivor (CAYACS) Research Program. Pediatr Blood Cancer 2013; 60: 816–822.

    Article  Google Scholar 

  11. Khera N, Storer B, Flowers ME, Carpenter PA, Inamoto Y, Sandmaier BM et al. Nonmalignant late effects and compromised functional status in survivors of hematopoietic cell transplantation. J Clin Oncol 2012; 30: 71–77.

    Article  Google Scholar 

  12. Compton WM, Conway KP, Stinson FS, Grant BF . Changes in the prevalence of major depression and comorbid substance use disorders in the United States between 1991-1992 and 2001-2002. Am J Psychiatry 2006; 163: 2141–2147.

    Article  Google Scholar 

  13. Perou R, Bitsko RH, Blumberg SJ, Pastor P, Ghandour RM, Gfroerer JC et al. Mental health surveillance among children—United States, 2005-2011. MMWR Surveill Summ 2013; 62: 1–35.

    Google Scholar 

  14. Kazak AE, Derosa BW, Schwartz LA, Hobbie W, Carlson C, Ittenbach RF et al. Psychological outcomes and health beliefs in adolescent and young adult survivors of childhood cancer and controls. J Clin Oncol 2010; 28: 2002–2007.

    Article  Google Scholar 

  15. Simon GE, Von KM, Saunders K, Miglioretti DL, Crane PK, van BG et al. Association between obesity and psychiatric disorders in the US adult population. Arch Gen Psychiatry 2006; 63: 824–830.

    Article  Google Scholar 

Download references


Supported in part by the National Cancer Institute (CA 018029, HL 36444, CA 15704, CA 160684 and CA 78902). We are thankful to the FHCRC Long-term Follow-up staff and to our patients and their physicians who participate in our long-term follow-up program.

Author information

Authors and Affiliations


Corresponding author

Correspondence to K S Baker.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Hoffmeister, P., Storer, B., Syrjala, K. et al. Physician-diagnosed depression and suicides in pediatric hematopoietic cell transplant survivors with up to 40 years of follow-up. Bone Marrow Transplant 51, 153–156 (2016).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links