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Treatment of poor graft function after allogeneic hematopoietic cell transplantation with a booster of CD34-selected cells infused without conditioning

Bone Marrow Transplantation volume 49, pages 720–721 (2014)Cite this article

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Graft failure (GF) after allo-SCT is a serious complication with high mortality.1, 2 Discrimination between rejection and poor graft function (PGF) can be made by chimerism analysis. In rejection, chimerism status is mixed, with the presence of recipient cells, whereas full donor chimerism is present in PGF. In patients with rejection, a second transplant preceded by a conditioning regimen should be considered.1, 2, 3

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Authors and Affiliations

  1. Department Of Hematology, National University Hospital, Copenhagen, Denmark

    B Askaa, L Vindeløv & H Sengeløv

  2. Department of Clinical Immunology, National University Hospital, Copenhagen, Denmark

    A Fischer-Nielsen & E K Haastrup

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  1. B Askaa
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  2. A Fischer-Nielsen
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  3. L Vindeløv
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Correspondence to H Sengeløv.

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Askaa, B., Fischer-Nielsen, A., Vindeløv, L. et al. Treatment of poor graft function after allogeneic hematopoietic cell transplantation with a booster of CD34-selected cells infused without conditioning. Bone Marrow Transplant 49, 720–721 (2014). https://doi.org/10.1038/bmt.2014.5

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