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Persistence of high-level (1,3)-β-D-glucan after candidemia following autologous peripheral SCT in a pediatric patient

Bone Marrow Transplantation volume 50, pages 137–138 (2015)Cite this article

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1,3-β-D-Glucan (BDG) is a cell wall component of several fungal pathogens, including Candida and Aspergillus. Many studies have shown that evaluation of plasma BDG could be a useful test for diagnosis of invasive fungal disease (IFD) in adults with hematologic malignancies when combined with clinical, radiological and microbiological findings.1, 2, 3

However scanty data are available in pediatrics, and these are derived from healthy subjects or small case series of immunocompromised children with otherwise documented IFD.4, 5, 6, 7, 8, 9, 10

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Authors and Affiliations

  1. Infectious Diseases Unit, Istituto Giannina Gaslini—Ospedale Pediatrico IRCCS, Genova, Italy

    A Naselli & E Castagnola

  2. Hemopoietic Stem Cell Transplant Unit, Istituto Giannina Gaslini—Ospedale Pediatrico IRCCS, Genova, Italy

    M Faraci, E Lanino & G Morreale

  3. Laboratory of Analysis, Istituto Giannina Gaslini—Ospedale Pediatrico IRCCS, Genova, Italy

    G Cangemi & R Bandettini

Authors
  1. A Naselli
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  2. M Faraci
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  3. E Lanino
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  4. G Morreale
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  5. G Cangemi
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  6. R Bandettini
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  7. E Castagnola
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Correspondence to E Castagnola.

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Naselli, A., Faraci, M., Lanino, E. et al. Persistence of high-level (1,3)-β-D-glucan after candidemia following autologous peripheral SCT in a pediatric patient. Bone Marrow Transplant 50, 137–138 (2015). https://doi.org/10.1038/bmt.2014.206

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