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Hematopoietic SCT for adult T-cell leukemia/lymphoma: a review

Bone Marrow Transplantation volume 46, pages 1039–1044 (2011)Cite this article

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Abstract

Adult T-cell leukemia/lymphoma is a T-cell malignancy caused by the human T-cell lymphotropic virus type 1. The aggressive forms of the disease carry a poor prognosis with standard therapies. The role of high-dose treatment with blood and marrow transplantation has, therefore, been examined mainly by Japanese groups in the form of retrospective studies. In this study, we review the literature, discuss some of the challenges facing successful transplantation approaches and stress the need for more innovative studies including in the Western hemisphere.

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Acknowledgements

We thank Dr Shuichi Taniguchi and Dr Koji Kato for their input, and Miss Priscilla DaSilva for her secretarial assistance.

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Authors and Affiliations

  1. Division of Hematological Malignancies and Blood and Marrow Transplantation, Roger Williams Medical Center, Providence, RI, USA

    M Jabbour, H Tuncer, T Roy, J Pojani & A S Al-Homsi

  2. Boston University School of Medicine, Boston, MA, USA

    M Jabbour, H Tuncer & A S Al-Homsi

  3. Division of Hematology and Medical Oncology, Lifespan and Alpert Medical School, Brown University, Providence, RI, USA

    J Castillo & J Butera

  4. Department of Medicine, Our Lady of Fatima Hospital, North Providence, RI, USA

    M Al-Malki

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  1. M Jabbour
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Correspondence to A S Al-Homsi.

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Jabbour, M., Tuncer, H., Castillo, J. et al. Hematopoietic SCT for adult T-cell leukemia/lymphoma: a review. Bone Marrow Transplant 46, 1039–1044 (2011). https://doi.org/10.1038/bmt.2011.27

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