Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Successful treatment of isohemagglutinin-mediated pure red cell aplasia after ABO-mismatched allogeneic hematopoietic cell transplant using bortezomib

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2

References

  1. O’Donnell MR . Blood group Incompatibilities and hemolytic complications of hematopoietic cell transplantation. In: Appelbaum FR, Forman SJ, Negrin RS, Blume KG (eds). Thomas’ Hematopoietic Cell Transplantation, 4th edn, Wiley-Blackwell: Chichester, West Sussex, UK, 2008, pp 1219–1225.

    Google Scholar 

  2. Mielcarek M, Leisenring W, Torok-Storb B, Storb R . Graft-versus-host disease and donor-directed hemagglutinin titers after ABO-mismatched related and unrelated marrow allografts: evidence for a graft-versus-plasma cell effect. Blood 2000; 96: 1150–1156.

    CAS  PubMed  Google Scholar 

  3. Gmur JP, Burger J, Schaffner A, Neftel K, Oelz O, Frey D et al. Pure red cell aplasia of long duration complicating major ABO-incompatible bone marrow transplantation. Blood 1990; 75: 290–295.

    CAS  PubMed  Google Scholar 

  4. Fang B, Song Y, Li N, Li J, Han Q, Zhao RC . Mesenchymal stem cells for the treatment of refractory pure red cell aplasia after major ABO-incompatible hematopoietic stem cell transplantation. Ann Hematol 2009; 88: 261–266.

    Article  Google Scholar 

  5. Raab MS, Podar K, Breitkreutz I, Richardson PG, Anderson KC . Multiple myeloma. Lancet 2009; 374: 324–339.

    Article  Google Scholar 

  6. Kane RC, Dagher R, Farrell A, Ko CW, Sridhara R, Justice R et al. Bortezomib for the treatment of mantle cell lymphoma. Clin Cancer Res 2007; 13: 5291–5294.

    Article  CAS  Google Scholar 

  7. Carson KR, Beckwith LG, Mehta J . Successful treatment of IgM-mediated autoimmune hemolytic anemia with bortezomib. Blood 2010; 115: 915.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We thank Dr Jayesh Mehta (The Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, USA) and Dr Rainer Storb (Fred Hutchinson Cancer Research Center, University of Washington, Seattle, USA) for their invaluable advice given in the management of this case.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L P Koh.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Poon, LM., Koh, L. Successful treatment of isohemagglutinin-mediated pure red cell aplasia after ABO-mismatched allogeneic hematopoietic cell transplant using bortezomib. Bone Marrow Transplant 47, 870–871 (2012). https://doi.org/10.1038/bmt.2011.176

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/bmt.2011.176

This article is cited by

Search

Quick links