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ECIL 3-2009 update guidelines for antifungal management

Bone Marrow Transplantation volume 47, page 866 (2012)Cite this article

We thank a lot the ECIL group for updating the antifungal guidelines for fungal management in leukemia patients and those undergoing SCT and for providing useful data to treat them in the best way.1

Based on preliminary results of a randomized study comparing voriconazole with fluconazole the latter is positioned as provisional AI score for prophylaxis after allogeneic transplantation.2 This paper has been published in extenso, and the fungal free survival at 180 days (primary end point of the study) was similar in patients prophylaxed with voriconazole or fluconazole (78 vs 75%).

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References

  1. Maertens J, Marchetti O, Herbrecht R, Cornely OA, Flückiger U, Frêre P et al. European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3-2009 update. Bone Marrow Transplant 2011; 46: 709–718.

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  2. Wingard JR, Carter SL, Walsh TJ, Kurtzberg J, Small TN, Baden LR et al. Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation. Blood 2010; 116: 5111–5118.

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  4. Girmenia C, Barosi G, Aversa F, Bacigalupo A, Barbui T, Baronciani D et al. Prophylaxis and treatment of invasive fungal diseases in allogeneic stem cell transplantation: results of a consensus process by Gruppo Italiano Trapianto di Midollo Osseo (GITMO). Clin Infect Dis 2009; 49: 1226–1236.

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Authors and Affiliations

  1. Department of Hematology, Humanitas Cancer Center, Istituto Clinico Humanitas, Rozzano, Italy

    L Castagna, S Bramanti, B Sarina, E Todisco, A Ibatici & A Santoro

Authors
  1. L Castagna
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  2. S Bramanti
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  3. B Sarina
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  4. E Todisco
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  5. A Ibatici
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  6. A Santoro
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Correspondence to L Castagna.

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The authors declare no conflict of interest.

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Castagna, L., Bramanti, S., Sarina, B. et al. ECIL 3-2009 update guidelines for antifungal management. Bone Marrow Transplant 47, 866 (2012). https://doi.org/10.1038/bmt.2011.154

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