Table 1 Patient demographics and mobilization history

From: Plerixafor plus granulocyte CSF can mobilize hematopoietic stem cells from multiple myeloma and lymphoma patients failing previous mobilization attempts: EU compassionate use data

  Myeloma Lymphoma All cases
No. of patients N (%) 32 (57) 24 (43) 56 (100)
Disease, N (%)
 Multiple myeloma 32 (100) 32 (57)
 Diffuse large B-Cell NHL 9 (37) 9 (16)
 Follicular NHL 7 (29) 7 (12)
 Mantle cell NHL 6 (25) 6 (11)
 Hodgkin's lymphoma 2 (8) 2 (4)
Age (years)
 Median 62 57 60
 Min–Max 34–69 33–64 33–69
 Mean (s.d.) 60.7 (7.2) 52.9 (10.1) 57.4 (9.3)
Sex, N (%)
 Female 16 (50) 11 (46) 27 (48)
 Male 16 (50) 13 (54) 29 (52)
Wt (kg)
 Median 73 75 74
 Min–Max 50–108 57–116 50–116
 Mean (s.d.) 73.6 (15.6) 77.6 (15.7) 75.3 (15.6)
No. of previous lines of therapy
 Median 2 2 2
 Min–Max 1–6 1–10 1–10
 Mean (s.d.) 2.2 (1.4) 3.1 (2.0) 2.6 (1.7)
Previous attempts 37 36 73
 Median 1 1 1
 Min–Max 0–2 0–3 0–3
 Mean (s.d.) 1.2 (0.5) 1.4 (0.7) 1.3 (0.6)
Previous attempts: no. and type 37 36 73
 G-CSF alone 9 (24) 19 (53) 28 (38)
 Chemotherapy+G-CSF 28 (76) 15 (42) 43 (59)
 SCF+G-CSF 2 (5) 2 (3)
Previous CD34 cells collected
 No. of patients N (%) 9 (28) 10 (42) 19 (34)
 Median 1.16 0.61 0.77
 Min–Max 0.68–1.48 0.16–0.83 0.16–1.48
 Mean (s.d.) 1.09 (0.30) 0.53 (0.25) 0.79 (0.39)
Baseline HB (g per 100 ml)
 Median 11.5 12.3 11.9
 Min–Max 8.8–15.3 8.7–15.1 8.7–15.3
 Mean (s.d.) 11.8 (1.5) 12.1 (1.8) 11.9 (1.6)
Baseline PLT ( × 10 9 per L)
 Median 216.0 155.5 186.0
 Min–Max 89.0–434.0 55.0–370.0 55.0–434.0
 Mean (s.d.) 219.3 (82.2) 158.4 (75.6) 192.8 (84.2)
Baseline WBC ( × 10 9 per L)
 Median 4.7 4.8 4.7
 Min–Max 2.5–21.6 1.4–19.9 1.4–21.6
 Mean (s.d.) 5.7 (3.7) 5.6 (3.8) 5.7 (3.7)
Baseline ANC ( × 10 9 per L)
 Median 2.5 2.9 2.7
 Min–Max 1.5–16.0 0.5–6.2 0.5–16.0
 Mean (s.d.) 3.9 (3.4) 3.0 (1.5) 3.5 (2.7)
  1. Abbreviations: NHL=non-Hodgkin's lymphoma; PLT=plt count.