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Microbial Issues

Infections with the 2009 H1N1 influenza virus among hematopoietic SCT recipients: a single center experience

Bone Marrow Transplantation volume 46, pages 1430–1436 (2011)Cite this article

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Abstract

We retrospectively reviewed medical records of 39 hematopoietic SCT (HSCT) recipients who presented at our hospital between 1 October 2009 and 31 January 2010 with the 2009 H1N1 influenza infection. The median age at presentation was 13.8 years (range: 3.3–56.9), infections developed at a median of 585 days (range: 0–2316) post transplant, the majority (n=27, 69%) occurred in allogeneic HSCT recipients, 12 (31%) patients were on immunosuppressive therapy and 12 (31%) had GVHD. Lower airway disease was present in 8 patients (21%). In total, 15 patients (39%) were hospitalized with a median duration of 4.5 days (range: 3–27 days) and 3 (8%) required mechanical ventilation; 2 of whom died.

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Acknowledgements

We acknowledge the King Hussein Cancer Foundation for their support to KHCC.

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Authors and Affiliations

  1. Bone Marrow and Stem Cell Transplantation program, King Hussein Cancer Center (KHCC), Amman, Jordan

    R Rihani, L Ghatasheh, F Abdel-Rahman, N Hussein, A Hussein, A Al-Zaben & M Sarhan

  2. Infection Control Program, King Hussein Cancer Center (KHCC), Amman, Jordan

    W Hayajneh & M Saad

  3. Department of Pediatric Oncology, King Hussein Cancer Center (KHCC), Amman, Jordan

    I Sultan

  4. Department of Pediatrics, Jordan University for Science and Technology, Irbid, Jordan

    W Hayajneh

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  1. R Rihani
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  2. W Hayajneh
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Correspondence to M Saad.

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Rihani, R., Hayajneh, W., Sultan, I. et al. Infections with the 2009 H1N1 influenza virus among hematopoietic SCT recipients: a single center experience. Bone Marrow Transplant 46, 1430–1436 (2011). https://doi.org/10.1038/bmt.2010.329

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