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Future perspectives

Bone Marrow Transplantation volume 45, pages 843–845 (2010)Cite this article

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Successful transplantation with an HLA-identical sibling donor is now over 40 years old and unrelated volunteer donors have been used for 25 years. Tens of thousands of people are alive today because of this relatively new therapeutic modality. However, hematopoietic SCT (HSCT) has not yet properly come of age, as only a minority of patients in need of an HSCT receive one and over half of those who received a transplant died within a few years of transplantation.

Hence, in this epilogue, we will first discuss new developments in donor selection, emphasizing that as an adult HLA fully matched donor is not always available, an HLA-mismatched donor may in some instances provide an alternative with at least equivalent results.

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Authors and Affiliations

  1. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

    J J van Rood

  2. Anthony Nolan Trust and Imperial College, London, UK

    J M Goldman

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  1. J J van Rood
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  2. J M Goldman
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Correspondence to J M Goldman.

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van Rood, J., Goldman, J. Future perspectives. Bone Marrow Transplant 45, 843–845 (2010). https://doi.org/10.1038/bmt.2010.1

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