Table 4 Selected site–specific SIRs and 95% CIs of a cancer diagnosis among patients with a hospital diagnosis of epistaxis or haemoptysis, Denmark 1995–2013
From: Risk of cancer in patients with epistaxis and haemoptysis
| Epistaxis | Haemoptysis | |||||
|---|---|---|---|---|---|---|
| Cancer site | Obs | Exp | SIR (95% CI) | Obs | Exp | SIR (95% CI) |
| All malignant neoplasms | 9173 | 7737 | 1.19 (1.16, 1.21) | 2582 | 1540 | 1.68 (1.61, 1.74) |
| Hodgkin’s lymphoma | 9 | 16 | 0.57 (0.26, 1.08) | 6 | 3 | 1.82 (0.67, 3.97) |
| Non-Hodgkin’s lymphoma | 240 | 188 | 1.28 (1.12, 1.45) | 52 | 38 | 1.37 (1.03, 1.80) |
| Multiple myeloma | 97 | 71 | 1.36 (1.10, 1.66) | 26 | 14 | 1.89 (1.23, 2.77) |
| Leukaemia | 224 | 160 | 1.40 (1.22, 1.59) | 41 | 29 | 1.40 (1.01, 1.90) |
| Liver | 146 | 68 | 2.16 (1.82, 2.54) | 39 | 13 | 2.92 (2.07, 3.99) |
| Malignant melanoma | 204 | 202 | 1.01 (0.88, 1.16) | 31 | 47 | 0.66 (0.45, 0.93) |
| Non-melanoma skin cancer | 2165 | 2049 | 1.06 (1.01, 1.10) | 442 | 405 | 1.09 (0.99, 1.20) |
| Cervix | 61 | 33 | 1.83 (1.40, 2.35) | NA | ||
| Anus and anal canal excluding malignant melanomas | 12 | 15 | 0.82 (0.42, 1.43) | NA | ||
| External female genitals excluding basal cell carcinomas | 17 | 14 | 1.21 (0.70, 1.93) | NA | ||
| Lip | 12 | 12 | 1.03 (0.53, 1.80) | 5 | 2 | 2.62 (0.85, 6.10) |
| Tongue | 50 | 22 | 2.27 (1.69, 3.00) | 17 | 5 | 3.30 (1.92, 5.29) |
| Mouth | 86 | 37 | 2.32 (1.86, 2.87) | 12 | 8 | 1.47 (0.76, 2.58) |
| Tonsil and pharynx | 142 | 53 | 2.70 (2.28, 3.18) | 35 | 14 | 2.56 (1.78, 3.56) |
| Other and poorly specified location in lip, oral cavity, or pharynx | NA | 26 | 11 | 2.30 (1.50, 3.36) | ||
| Larynx | 77 | 52 | 1.47 (1.16, 1.84) | NA | ||
| Oesophagus | 123 | 94 | 1.31 (1.09, 1.56) | 28 | 19 | 1.51 (1.00, 2.18) |
| Stomach | 121 | 118 | 1.02 (0.85, 1.22) | 26 | 22 | 1.18 (0.77. 1.73) |
| Colon including rectosigmoid junction | 641 | 592 | 1.08 (1.00, 1.17) | 118 | 105 | 1.12 (0.93. 1.34) |
| Rectum | 289 | 301 | 0.96 (0.85, 1.08) | 52 | 58 | 0.90 (0.68. 1.19) |
| Pancreas | 204 | 184 | 1.11 (0.96, 1.27) | 49 | 35 | 1.42 (1.05. 1.87) |
| Lung, bronchus, and trachea | 1183 | 815 | 1.45 (1.37, 1.54) | 958 | 163 | 5.87 (5.51. 6.26) |
| Kidney | 188 | 117 | 1.60 (1.38, 1.85) | 45 | 25 | 1.81 (1.32. 2.42) |
| Renal pelvis | 15 | 15 | 1.02 (0.57, 1.68) | NA | ||
| Ureter | 6 | 5 | 1.27 (0.46, 2.76) | NA | ||
| Urinary bladder | 214 | 220 | 0.97 (0.84, 1.11) | 33 | 38 | 0.86 (0.59, 1.21) |
| Salivary gland | 12 | 9 | 1.28 (0.66, 2.23) | NA | ||
| Small intestine | 20 | 16 | 1.23 (0.75, 1.90) | 6 | 4 | 1.71 (0.63, 3.74) |
| Gallbladder and bile ducts | 50 | 41 | 1.22 (0.91, 1.61) | 14 | 7 | 1.91 (1.04, 3.20) |
| Nasal cavity, middle ear, and accessory sinuses | 55 | 13 | 4.28 (3.23, 5.57) | NA | ||
| Pleura including mesothelioma pleura | 16 | 24 | 0.67 (0.38, 1.09) | 8 | 5 | 1.70 (0.73, 3.34) |
| Bone and articular cartilage | 9 | 6 | 1.58 (0.72, 3.00) | NA | ||
| Retroperitoneum and peritoneum, and malignant neoplasm of other connective and soft tissue | 35 | 34 | 1.03 (0.71, 1.43) | 9 | 7 | 1.25 (0.57, 2.37) |
| Breast | 645 | 559 | 1.15 (1.07, 1.25) | 136 | 137 | 0.99 (0.83, 1.18) |
| Uterus | 111 | 108 | 1.03 (0.85, 1.24) | 16 | 25 | 0.65 (0.37, 1.06) |
| Ovary and fallopian tube | 68 | 77 | 0.88 (0.68, 1.12) | 18 | 17 | 1.04 (0.61, 1.64) |
| Penis excluding basal cell carcinomas | 13 | 13 | 1.02 (0.54, 1.75) | 3 | 2 | 1.25 (0.26, 3.66) |
| Prostate | 1137 | 1002 | 1.13 (1.07, 1.20) | 200 | 187 | 1.07 (0.92, 1.23) |
| Testis | 29 | 31 | 0.95 (0.63, 1.36) | 5 | 8 | 0.66 (0.21, 1.54) |
| Eye and adnexa | 12 | 12 | 0.97 (0.50, 1.69) | NA | ||
| Brain including hypophysis, corpus pineale, and ductus craniopharyngealis | 79 | 74 | 1.07 (0.85, 1.34) | 21 | 16 | 1.31 (0.81, 2.01) |
| Endocrine glands and related structure | 27 | 23 | 1.15 (0.76, 1.67) | 14 | 6 | 2.37 (1.30, 3.98) |
| Metastasis and unspecified cancer in lymph nodes | 204 | 159 | 1.28 (1.11, 1.47) | 42 | 26 | 1.59 (1.15, 2.15) |
| Malignant neoplasm of other, ill-defined, or unspecified sites | 98 | 61 | 1.60 (1.30, 1.95) | 18 | 9 | 1.94 (1.15, 3.06) |
