Table 5 Adjusted HRa and 95% CI for associations between BMI trajectories, and oesophageal and gastric cardia adenocarcinoma incidence, NIH-AARP Diet and Health Study, and PLCO Cancer Screening Trial

From: Body weight trajectories and risk of oesophageal and gastric cardia adenocarcinomas: a pooled analysis of NIH-AARP and PLCO Studies

    Oesophageal adenocarcinoma Gastric cardia adenocarcinoma
  %, Population Non-cases ( n) Cases ( n) HR (95% CI) Cases ( n) HR (95% CI)
BMI trajectory
Normal BMI 42.8 168 026 167 Referent 114 Referent
Normal BMI to overweight 43.4 170 289 306 1.39 (1.15, 1.69) 203 1.42 (1.13, 1.79)
Normal BMI to obese 11.7 45 902 117 2.42 (1.90, 3.08) 54 1.69 (1.22, 2.35)
Overweight to obese 2.0 7948 14 2.90 (1.67, 5.04) 14 4.07 (2.32, 7.15)
  1. Abbreviations: BMI=body mass index; CI=confidence interval; HR=hazard ratio; PLCO=Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
  2. aAdjusted for sex, race (non-Hispanic white, non-Hispanic black, other), smoking (never/current/former, and categorised cigarettes per day (0, 1–10, 11–20, 21–30, 31–40, 41–60, 61+)), education (high school or less, technical school or some college, college graduate, postgraduate), and study.