Table 3: Differential expression analysis results for the 15 PAX8 pathway genes within 1 Mb of a P<10−5 risk SNPa

From: Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

 IGROV1 cellsHeyA8 cells
GeneP-valueFDRFold changeP-valueFDRFold change
TNF2.4E−050.0042.556.5E−030.0971.12
BNC26.1E−040.0241.163.8E−030.0681.16
HOXB77.6E−040.0281.227.3E−020.3741.06
NCL1.8E−030.0471.221.3E−040.0091.21
SP62.0E−020.1891.237.1E−010.9121.02
HOXB52.2E−020.2001.184.6E−010.7961.09
HOXB82.5E−020.2121.263.6E−010.7311.03
ATP5G15.4E−020.3251.123.4E−010.7191.07
WNT48.1E−020.3981.101.3E−010.4991.02
HOXD89.0E−020.4171.137.7E−010.9311.01
OSBPL72.6E−010.6581.052.7E−040.0141.26
HOXB45.3E−010.8421.021.4E−010.5101.10
SLC5A55.3E−010.8391.024.2E−010.7721.01
HOXD127.1E−010.9171.014.3E−010.7811.02
TERT9.6E−010.9891.005.8E−030.0901.16
  1. Abbreviations: FDR=false discovery rate; Mb=megabase; SNP=single-nucleotide polymorphism.
  2. aList sorted by IGROV1 P-value.