Table 1 Distribution of selected endometrial cancer risk factors by quintile of red meat intake among women in the NIH-AARP Diet and Health Study (N=111 356 in baseline cohort, N=72 796 in risk factor cohort)

From: A prospective investigation of fish, meat and cooking-related carcinogens with endometrial cancer incidence

  Quintiles of red meat intake, g per 1000 kcal
  1st 2nd 3rd 4th 5th
Baseline questionnaire, N (cases) 290 278 315 286 317
Daily red meat (g per 1000 kcal), mean (s.d.) 7.1 (3.6) 17.2 (2.5) 25.9 (2.6) 36.2 (3.6) 58.5 (15.7)
Daily white meat (g per 1000 kcal), mean (s.d.) 37.4 (34.3) 36.1 (27.9) 35.3 (24.6) 35.2 (23.5) 35.5 (23.1)
Daily processed meat (g per 1000 kcal), mean (s.d.) 3.4 (6.0) 5.5 (5.7) 7.4 (6.2) 9.8 (7.6) 14.5 (12.0)
Age in years, mean (s.d.) 61.8 (5.5) 61.9 (5.5) 61.8 (5.5) 61.5 (5.5) 61.1 (5.4)
Non- Hispanic White (N, %) 19 492 (87.5%) 20 090 (90.2%) 20 334 (91.3%) 20 621 (92.6%) 20 532 (92.2%)
Obese, BMI 30 kg m–2 (N, %) 3148 (14.1%) 4124 (18.5%) 4819 (21.6%) 5580 (25.1%) 6721 (30.1%)
Ever use of hormone therapy (N, %) 9329 (41.9%) 9307 (41.8%) 9106 (40.9%) 8763 (39.4%) 7959 (35.7%)
Ever use of oral contraceptives (N, %) 8641 (38.8%) 8815 (39.6%) 8915 (40.0%) 9131 (41.0%) 9290 (41.7%)
Age at menarche 10 years (N, %) 1408 (6.3%) 1297 (5.8%) 1360 (6.1%) 1275 (5.7%) 1492 (6.7%)
Age at first birth 30 years (N, %) 1727 (7.8%) 1574 (7.1%) 1672 (7.5%) 1561 (7.0%) 1522 (6.8%)
Nulliparous (N, %) 4276 (19.2%) 3907 (17.5%) 3648 (16.4) 3700 (16.6%) 3751 (16.8%)
Age at menopause 55 years (N, %) 2452 (11.0%) 2332 (10.5%) 2199 (9.9%) 2169 (9.7%) 2137 (9.6%)
Current smoker (N, %) 1790 (8.0%) 2627 (11.8%) 3128 (14.0%) 3772 (16.9%) 4548 (20.4%)
Physical exercise 1 time per week (N, %) 16 101 (72.3%) 15 000 (67.4%) 14 019 (62.9%) 13 147 (59.0%) 11 770 (52.9%)
Energy (kcal day–1) 1530 (630) 1531 (623) 1553 (631) 1592 (645) 1634 (681)
Risk factor questionnaire, N (cases) 194 191 214 187 209
DiMeIQx (ng per 1000 kcal day–1), mean (s.d.) 0.24 (0.8) 0.37 (0.8) 0.49 (0.9) 0.67 (1.2) 1.1 (2.6)
MeIQx (ng per 1000 kcal day–1), mean (s.d.) 2.2 (3.3) 4.9 (6.1) 7.3 (8.6) 10.5 (12.7) 18.4 (25.6)
PhIP (ng per 1000 kcal day–1), mean (s.d.) 24.0 (63.8) 31.3 (59.9) 37.3 (60.1) 47.2 (69.6) 72.3 (106.2)
BaP (ng per 1000 kcal day–1), mean (s.d.) 4.5 (11.7) 7.5 (12.6) 10.3 (14.9) 14.4 (19.0) 23.7 (34.4)
  1. Abbreviations: BaP=benzo(a)pyrene; BMI=body mass index; DiMeIQx=2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline; MeIQx=2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline; PhIP=2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.