Figure 7 | British Journal of Cancer

Figure 7

From: Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma

Figure 7

Effect of si- HDAC1 transfectants on cell proliferation, cell cycle and apoptosis in SAS cells. (A) Suppression of cell proliferation after transfection of si-HDAC1_1 and si-HDAC1_2 into SAS cells as determined by XTT assay. (B) Typical results of cell cycle analysis of si-control, si-HDAC1_1 and si-HDAC1_2 transfectants. The bar chart represents the percentage of the cells in the G0/G1, S or G2/M phase. (C) Typical results of cell apoptosis analysis of mock, si-control, si-HDAC1_1 and si-HDAC1_2 transfectants. Trials were independently conducted three times. *P<0.0167, **P<0.01, ***P<0.0001.

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